Molla Yohannis Derbew, Kassa Samrawit Andargie, Tadesse Amanuel Kassa
Department of Surgery, University of Gondar, Collage of Medicine and Health Sciences, Gondar, Ethiopia.
Department of Surgery, University of Gondar, Collage of Medicine and Health Sciences, Gondar, Ethiopia.
Int J Surg Case Rep. 2023 Apr;105:108080. doi: 10.1016/j.ijscr.2023.108080. Epub 2023 Mar 28.
Intestinal tuberculosis (TB) comprises of about 5 % of all cases of tuberculosis in susceptible communities. Intestinal tuberculosis establishes itself in the lymphoid follicles of the Peyer's patches and spreads to the submucosal and subserosal planes. A gastroduodenal location for TB is very rare even in patients with pulmonary TB and gastroduodenal TB lesions are usually secondary.
A 48 year old Ethiopian patient presented with non-bilious, non-projectile vomiting of ingested matter which progressively worsens over time. Associated with this he had burning type of epigastric pain for which he had been treated with antiulcer drugs on multiple occasion, but he had no improvement. The vomiting worsened over the past year and he had unquantified but significant weight loss. Subsequently the patient was diagnosed with duodenal TB and was treated with antituberculous drugs according to the national protocol for six months and the above symptoms subsided. The patient had significant weight gain after starting treatment.
The commonest site for gastro-intestinal tuberculosis (TB) is the ileocecal region and duodenal tuberculosis constitutes around 2 % of cases of abdominal tuberculosis. A high index of suspicion for tuberculosis is required in any patient with gastrointestinal symptoms living in endemic areas.
We suggest that a diagnosis of duodenal tuberculosis should always be considered in young patients presenting with gastric outlet obstruction (GOO) or unresponsive or relapsing dyspepsia, in areas where tuberculosis is endemic.
在易感人群中,肠结核约占所有结核病病例的5%。肠结核在派尔集合淋巴结的淋巴滤泡中发病,并蔓延至黏膜下层和浆膜下层。即使在肺结核患者中,胃十二指肠结核的发病部位也非常罕见,胃十二指肠结核病变通常是继发性的。
一名48岁的埃塞俄比亚患者出现非胆汁性、非喷射性的摄入物呕吐症状,且随着时间的推移逐渐加重。与此相关的是,他有烧灼样上腹部疼痛,为此他曾多次接受抗溃疡药物治疗,但没有改善。在过去一年里呕吐症状恶化,他出现了未量化但明显的体重减轻。随后,该患者被诊断为十二指肠结核,并根据国家方案接受了六个月的抗结核药物治疗,上述症状消失。开始治疗后,患者体重显著增加。
胃肠道结核最常见的部位是回盲部,十二指肠结核约占腹部结核病例的2%。在结核病流行地区,任何有胃肠道症状的患者都需要高度怀疑患有结核病。
我们建议,在结核病流行地区,对于出现胃出口梗阻(GOO)或无反应或复发性消化不良的年轻患者,应始终考虑十二指肠结核的诊断。