Swanson G M, Satariano E R, Satariano W A, Threatt B A
College of Human Medicine, Michigan State University, East Lansing 48824.
Cancer. 1990 Sep 15;66(6):1297-301. doi: 10.1002/1097-0142(19900915)66:6<1297::aid-cncr2820660633>3.0.co;2-m.
This population-based study presents trends in stage at diagnosis of invasive female breast cancer during the decade from 1978 to 1987 in the Detroit metropolitan area. Its purpose is to determine whether there has been an increase in early breast cancers: those that are smaller than 2 cm at diagnosis and have no axillary lymph node involvement. Trend analyses of tumor size, node status, year of diagnosis, age, and race were performed for 17,216 incident cases drawn from the Metropolitan Detroit Cancer Surveillance System (MDCSS). Although trends toward earlier diagnosis of breast cancer are observed, less improvement is seen for black women than white women in the presentation of breast cancer at smaller, node-free stages. Implications for breast cancer screening are discussed.
这项基于人群的研究呈现了1978年至1987年这十年间底特律都会区浸润性女性乳腺癌确诊时的分期趋势。其目的是确定早期乳腺癌（即确诊时小于2厘米且无腋窝淋巴结受累的乳腺癌）是否有所增加。对从底特律都会区癌症监测系统（MDCSS）提取的17216例新发病例进行了肿瘤大小、淋巴结状态、确诊年份、年龄和种族的趋势分析。尽管观察到乳腺癌早期诊断的趋势，但在较小、无淋巴结转移阶段的乳腺癌表现方面，黑人女性的改善程度低于白人女性。文中讨论了对乳腺癌筛查的启示。
