Richardson J L, Langholz B, Bernstein L, Burciaga C, Danley K, Ross R K
Department of Preventive Medicine, School of Medicine, University of Southern California, Los Angeles 90033.
Br J Cancer. 1992 Jun;65(6):922-6. doi: 10.1038/bjc.1992.193.
Information on 23,567 Non-Hispanic White, 2,539 Black, and 2,380 Hispanic breast cancer cases diagnosed between 1977 and 1985 was used to evaluate the risk of late stage diagnosis and long duration of symptoms prior to diagnosis in relation to ethnicity, socioeconomic status, age and year of diagnosis. All data were collected by the University of Southern California Cancer Surveillance Program, the comprehensive population-based incidence registry of Los Angeles County. The results indicate that lower socioeconomic status, Black or Hispanic ethnicity, younger age, and earlier year of diagnosis are risk factors for late stage diagnosis and long duration of symptoms. The effect of ethnicity was not explained by lower SES levels among Black or Hispanic women. After controlling for duration of symptoms, race and SES remained significantly predictive of more advanced stage. More recent diagnosis across the 9 year time frame was not associated with improved stage for those of low SES. These results suggest that increased efforts are needed to reach low SES and Black and Hispanic women with campaigns to improve the stage at which breast cancer is detected.
利用1977年至1985年间确诊的23567例非西班牙裔白人、2539例黑人及2380例西班牙裔乳腺癌病例的信息，评估晚期诊断风险以及诊断前症状持续时间与种族、社会经济地位、年龄和诊断年份之间的关系。所有数据由南加州大学癌症监测项目收集，该项目是洛杉矶县基于人群的综合发病率登记处。结果表明，社会经济地位较低、黑人或西班牙裔种族、年龄较小以及诊断年份较早是晚期诊断和症状持续时间较长的危险因素。黑人或西班牙裔女性中较低的社会经济地位水平并不能解释种族因素的影响。在控制症状持续时间后，种族和社会经济地位仍然显著预测更晚期阶段。在9年时间范围内，对于社会经济地位较低的人来说，更近的诊断与分期改善无关。这些结果表明，需要加大力度，通过开展活动，让社会经济地位较低的女性以及黑人及西班牙裔女性提高乳腺癌的检测分期。
