Park Ji Sook, Seo Ji Hyun, Youn Hee-Shang
Department of Pediatrics, Gyeongsang National University School of Medicine, Jinju, Korea.
Pediatr Gastroenterol Hepatol Nutr. 2013 Mar;16(1):22-7. doi: 10.5223/pghn.2013.16.1.22. Epub 2013 Mar 31.
The prevalence of obesity is increasing worldwide. Obesity can cause hyperlipidemia, hypertension, cardiovascular diseases, metabolic syndrome and non-alcoholic fatty liver disease (NAFLD). Many environmental or genetic factors have been suggested to contribute to the development of obesity, but there is no satisfactory explanation for its increased prevalence. This review discusses the latest updates on the role of the gut microbiota in obesity and NAFLD.
全球肥胖症的患病率正在上升。肥胖会导致高脂血症、高血压、心血管疾病、代谢综合征和非酒精性脂肪性肝病(NAFLD)。许多环境或遗传因素被认为与肥胖症的发生有关,但对于其患病率上升却没有令人满意的解释。本综述讨论了肠道微生物群在肥胖症和非酒精性脂肪性肝病中作用的最新进展。