Veselovský J, Kovácik L, Rehák S
Katedra biológie a ekológie cloveka Prírodovedeckej fakulty UK, Bratislava.
Cesk Oftalmol. 1990 Jul;46(4):293-300.
The authors revealed by chromatographic analysis that in the investigated tissues of the bovine eye a 3% aqueous pilocarpine solution 2.5 hours after the last instillations alters specifically the levels of different free amino acids. In the capsule and anterior coat an increase was observed and in the nucleus and posterior coat a decline of the total amount of these components. In the control and pilocarpine-treated capsule and in the lenticular nucleus glutamic acid, is present in the highest concentration and in the anterior and posterior coat of the lens aspartic acid and lysine.
作者通过色谱分析揭示,在牛眼的被研究组织中,末次滴注2.5小时后,3%的毛果芸香碱水溶液会特异性改变不同游离氨基酸的水平。在晶状体囊和前囊膜中观察到这些成分总量增加,而在晶状体核和后囊膜中则下降。在对照和毛果芸香碱处理的晶状体囊中以及晶状体核中,谷氨酸浓度最高,而在晶状体前囊膜和后囊膜中,天冬氨酸和赖氨酸浓度最高。