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[脊髓小脑变性的记忆功能障碍]

[Memory dysfunction of spinocerebellar degeneration].

作者信息

Hirono N, Yamadori A, Kameyama M, Mezaki T, Abe K

机构信息

Department of Neurology, Sumitomo Hospital.

出版信息

Rinsho Shinkeigaku. 1990 May;30(5):505-9.

PMID:2401111
Abstract

We evaluated Rey's auditory verbal learning test (AVLT) and Wechsler adult intelligence scale (WAIS) in 29 patients with spinocerebellar degeneration (SCD) younger than 65 years old. They showed a significant impairment in the recall subtest of AVLT. However in the recognition subtest, there was no significant impairment in the recall subtest of AVLT. However in the recognition subtest, there was no significant difference between the patients and the control subjects. The patients with SCD also showed a significant decrement in both VIQ and PIQ. The disturbance of recall memory did not correlate with the disturbance of VIQ. The disturbance of recall memory without that of recognition memory is considered to be a characteristic of subcortical dementia. Therefore we concluded that the patients with SCD may develop subcortical dementia and that the localization of the disturbance of recall memory and that of the disturbance of VIQ might be different.

摘要

我们对29名年龄小于65岁的脊髓小脑变性(SCD)患者进行了雷氏听觉词语学习测验(AVLT)和韦氏成人智力量表(WAIS)评估。他们在AVLT的回忆子测验中表现出显著损伤。然而,在识别子测验中,AVLT的回忆子测验没有显著损伤。不过在识别子测验中,患者与对照受试者之间没有显著差异。SCD患者在言语智商(VIQ)和操作智商(PIQ)方面也表现出显著下降。回忆记忆障碍与VIQ障碍不相关。无识别记忆障碍的回忆记忆障碍被认为是皮质下痴呆的一个特征。因此,我们得出结论,SCD患者可能会发展为皮质下痴呆,并且回忆记忆障碍和VIQ障碍的定位可能不同。

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