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儿童卡马西平诱发的药物超敏反应伴嗜酸性粒细胞增多和系统症状(DRESS)综合征:对脉冲式糖皮质激素治疗反应迅速

Carbamazepine-induced DRESS syndrome in a child: rapid response to pulsed corticosteroids.

作者信息

Teng Paul, Tan Boon

机构信息

Queensland Institute of Dermatology Greenslopes.

出版信息

Dermatol Online J. 2013 May 15;19(5):18170.

Abstract

DRESS syndrome is an idiosyncratic reaction to drugs, which can occur in both adults and children. To date there is no agreed upon criteria for its diagnosis; there is even less consensus on its management. We report the case of a 14- year-old boy with carbamazepine induced DRESS syndrome, predominantly involving the liver. He responded rapidly to high dose pulsed intravenous corticosteroids.

摘要

药物超敏反应伴嗜酸性粒细胞增多和系统症状(DRESS)综合征是一种对药物的特异反应,可发生于成人和儿童。迄今为止,尚无公认的诊断标准;在其治疗方面,共识更少。我们报告一例14岁男孩,因卡马西平诱发DRESS综合征,主要累及肝脏。他对高剂量脉冲静脉注射皮质类固醇迅速产生反应。

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