Kietzmann M, Hapke H J, Beeke M, Stehle S
Institut für Pharmakologie, Toxikologie und Pharmazie der Tierärztlichen Hochschule Hannover.
Dtsch Tierarztl Wochenschr. 1990 Jul;97(7):290-3.
The arylmethane dye malachite green oxalate is used as an antimycotic and antiparasitic substance for treatment of fish diseases. The therapeutical use of malachite green is not licensed by the German drug act. A decree fixes a limit of tolerance of 0.01 mg malachite green/kg food produced from fish. A so-called standard license will be prepared for malachite green as a drug for fishes. By trout and carp, malachite green is eliminated slowly. Therefore a long withdrawal time is necessary. The toxicology of the arylmethane dye and the low tolerance to observe in trout and carp is to mind.
芳基甲烷染料草酸孔雀石绿用作抗真菌和抗寄生虫物质，用于治疗鱼类疾病。德国药品法未批准孔雀石绿的治疗用途。一项法令规定了鱼类生产食品中孔雀石绿的耐受限量为0.01毫克/千克。将为作为鱼类药物的孔雀石绿制定所谓的标准许可。孔雀石绿在鳟鱼和鲤鱼体内消除缓慢。因此需要较长的停药期。要注意芳基甲烷染料的毒理学以及在鳟鱼和鲤鱼中观察到的低耐受性。
