Koga Taketo, Matsukubo Takashi, Okuda Katsuji, Ishihara Kazuyuki
*Private Practice in Implant Dentistry, Chiba, Japan. †Professor and Chairman of Department of Epidemiology and Public Health, Tokyo Dental College, Chiba, Japan. ‡Professor of Department of Microbiology, Tokyo Dental College, Chiba, Japan. §Professor and Chairman of Department of Microbiology, Tokyo Dental College, Chiba, Japan.
Implant Dent. 2013 Oct;22(5):525-9. doi: 10.1097/ID.0b013e3182a2b8e3.
The objective of this study was to investigate the relationship between various clinical factors and bacterial contamination of bone chips (BC) collected during dental implant surgery and to elucidate how bacterial contamination might be minimized.
Implants were installed in 55 partially edentulous patients (36 men and 19 women), among whom the relationship between various clinical factors and bacterial contamination of BC collected by bone trap was investigated in 37. The effect of rinsing with a saline on BC was determined in 18 patients. Number of contaminating microorganisms was expressed as colony-forming units (CFUs).
CFUs in the maxilla were lower than those in the mandible (P < 0.01). CFUs at the incisors or canines were lower than those at the premolars or molars (P < 0.01). Logistic regression analysis revealed a relationship between average bacterial count and duration of surgery (odds ratio, 1.046; 95% CI, 1.012-1.081). Rinsing of BC reduced bacterial contamination.
Duration of surgery is a major clinical factor affecting contamination risk in BC, and rinsing of BC with a sterile saline solution reduces bacterial number.
本研究的目的是调查各种临床因素与牙种植手术期间收集的骨屑（BC）细菌污染之间的关系，并阐明如何将细菌污染降至最低。
对55例部分牙列缺损患者（36例男性和19例女性）进行种植体植入，其中37例研究了各种临床因素与通过骨收集器收集的BC细菌污染之间的关系。在18例患者中确定了用生理盐水冲洗对BC的影响。污染微生物的数量以菌落形成单位（CFU）表示。
上颌骨的CFU低于下颌骨（P < 0.01）。切牙或尖牙处的CFU低于前磨牙或磨牙处（P < 0.01）。逻辑回归分析显示平均细菌计数与手术持续时间之间存在关联（优势比，1.046；95%可信区间，1.012 - 1.081）。BC冲洗可减少细菌污染。
手术持续时间是影响BC污染风险的主要临床因素，用无菌生理盐水冲洗BC可减少细菌数量。
