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经动脉使用Onyx治疗腔内修复术后持续存在的II型内漏的中期结果。

Midterm results of the transarterial use of Onyx in the treatment of persisting type II endoleaks after EVAR.

作者信息

Bosiers M J, Schwindt A, Donas K P, Torsello G

机构信息

Department of Vascular Surgery, St. Franziskus Hospital Münster, Clinic for Vascular and Endovascular SurgeryMünster University Hospital, Münster, Germany -

出版信息

J Cardiovasc Surg (Torino). 2013 Aug;54(4):469-75.

Abstract

AIM

Type II endoleaks with growing aneurysm sac >5 mm in diameter after EVAR require treatment. Different treatment options have been reported. The aim of this study was to evaluate the use of an ethylene-vinyl alcohol copolymer (Onyx) in an endovascular approach.

METHODS

Between January 2010 and December 2011, 10 consecutive patients with persistent type II endoleaks leading to aneurysm growth >5 mm were treated in our center by transarterial Onyx embolization by super selective cannulation of the endoleak with microcatheters. Technical success was defined as transarterial Onyx deployment directly into the aneurysm sac. Clinical success was defined as stable or shrinking axial aneurysmal diameter during follow- up using an angiographic computed tomography.

RESULTS

Ten patients with 13 persistent type II endoleaks leading to aneurysm sac growth of >5 mm were identified in the time period. Technical success was 92% (12/13 patients). Two patients underwent a staged procedure because several, unconnected type II endoleaks were present. In one patient a cannulation of the inflow vessel responsible for the endoleak was not possible, continued efforts led to a rupture of the hypogastric artery which was treated by covered stent implantation. In one patient an extravasation of onyx out of the aneurysm sac into the inferior vena cava during the embolization process made a transvenous goose snare maneuver necessary to retrieve the dislocated copolymer. No further complications were observed during the mean follow-up of 19.8 months (range, 3-31 months). In all patients with successful embolization the aneurysm sac remained stable or was decreased within the follow-up period.

CONCLUSION

Use of Onyx in the endovascular treatment of type II endoleaks after EVAR is feasible, safe when accurately deployed and efficient. Further studies are necessary to evaluate the value of the different treatment modalities (translumbar vs. transarterial).

摘要

目的

腔内血管修复术(EVAR)后动脉瘤囊直径增长超过5mm的Ⅱ型内漏需要治疗。已有多种不同的治疗方案被报道。本研究的目的是评估乙烯-乙烯醇共聚物(Onyx)在血管内治疗方法中的应用。

方法

在2010年1月至2011年12月期间,我们中心对10例因持续性Ⅱ型内漏导致动脉瘤增长超过5mm的连续患者,通过微导管超选择性插管至内漏处,经动脉进行Onyx栓塞治疗。技术成功定义为经动脉将Onyx直接置入动脉瘤囊内。临床成功定义为在随访期间使用血管造影计算机断层扫描显示动脉瘤轴向直径稳定或缩小。

结果

在此期间共确定了10例患者存在13处导致动脉瘤囊增长超过5mm的持续性Ⅱ型内漏。技术成功率为92%(12/13例患者)。2例患者因存在多个不相连的Ⅱ型内漏而接受了分期手术。1例患者无法对导致内漏的流入血管进行插管,持续操作导致髂内动脉破裂,随后通过植入覆膜支架进行治疗。1例患者在栓塞过程中Onyx从动脉瘤囊外渗至下腔静脉,因此需要进行经静脉鹅颈圈套器操作以取出移位的共聚物。在平均19.8个月(范围3 - 31个月)的随访期间未观察到其他并发症。在所有成功栓塞的患者中,动脉瘤囊在随访期内保持稳定或缩小。

结论

Onyx用于EVAR术后Ⅱ型内漏的血管内治疗是可行的,准确置入时安全且有效。需要进一步研究以评估不同治疗方式(经腰动脉与经动脉)的价值。

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