CMP-唾液酸转运蛋白底物识别特性分析。
Characterisation of CMP-sialic acid transporter substrate recognition.
机构信息
Institute for Glycomics, Griffith University, Gold Coast Campus Queensland, 4222 (Australia).
出版信息
Chembiochem. 2013 Oct 11;14(15):1936-42. doi: 10.1002/cbic.201300298. Epub 2013 Sep 6.
PMID:24014346
Abstract
CMP-sialic acid transporter: We report an in-depth, multidisciplinary, structural study that has identified the amino acid residues intimately involved in CMP-sialic acid transporter (CST) substrate specificity. Our data provide a significant contribution towards a better understanding the structure-function relationship of this important family of transporters and the rational design of CST inhibitors.
摘要
CMP-唾液酸转运蛋白：我们报告了一项深入的、多学科的结构研究，该研究确定了与 CMP-唾液酸转运蛋白（CST）底物特异性密切相关的氨基酸残基。我们的数据为更好地理解这一重要转运蛋白家族的结构-功能关系以及 CST 抑制剂的合理设计提供了重要贡献。
Zotero 插件