尼日利亚 HIV 和乙型肝炎病毒合并感染患者通过瞬时弹性成像技术评估肝纤维化。
Assessment of liver fibrosis by transient elastography in patients with HIV and hepatitis B virus coinfection in Nigeria.
机构信息
Northwestern University, Chicago, Illinois.
出版信息
Clin Infect Dis. 2013 Dec;57(12):e189-92. doi: 10.1093/cid/cit564. Epub 2013 Sep 6.
Abstract
We describe the prevalence and risk factors for advanced liver fibrosis (≥9.3 kPa) using transient elastography in human immunodeficiency virus (HIV)–monoinfected and HIV/HBV (hepatitis B virus)–coinfected, antiretroviral naive adults in Nigeria. HBV coinfection and HBV DNA levels significantly increased the risk of advanced fibrosis in HIV and HIV/HBV patients, respectively.
摘要
我们描述了使用瞬态弹性成像技术在尼日利亚抗逆转录病毒治疗初治的人类免疫缺陷病毒（HIV）单感染和 HIV/乙型肝炎病毒（HBV）共感染的成人中，发生≥9.3kPa 的晚期肝纤维化的患病率和危险因素。HBV 共感染和 HBV DNA 水平分别显著增加了 HIV 和 HIV/HBV 患者发生晚期纤维化的风险。
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