Moon Myung-Sang, Kim Sung-SooS S, Moon Jeong-Lim, Kim Sung-Sim, Moon Hanlim
Department of Orthopedic Surgery, Cheju Halla General Hospital, Jeju, Korea.
J Orthop Surg (Hong Kong). 2013 Aug;21(2):209-12. doi: 10.1177/230949901302100219.
PURPOSE. To report on 23 patients with giant cell tumour (GCT) of the femur or tibia treated with curettage, electrocautery, burring, phenol irrigation, and cementation. METHODS. Records of these 14 men and 9 women aged 22 to 38 (mean, 31) years were reviewed. The most common site involved was the distal femur (n=13), followed by proximal tibia (n=8), proximal femur (n=1), and distal tibia (n=1). The lesions were classified as grade I (n=3), grade II (n=18), and grade III (n=2). Based on histology, the tumour stage was classified as grade I (n=5) and grade II (n=18). Two of these patients had recurrences, which were initially treated with simple curettage and bone grafting of the distal femur and distal tibia. RESULTS. The mean follow-up period was 5.7 (range, 2.5-10.1) years. 14 of the 23 patients were followed up for over 10 years. No patient developed any local recurrence, remote metastasis, or complication related to surgery or adjuvant therapy. CONCLUSION. Combined treatment entailing curettage, electrocautery, burring, phenol irrigation, and cementation was effective in treating GCT of bone.
目的。报告23例股骨或胫骨骨巨细胞瘤（GCT）患者接受刮除、电灼、磨钻、苯酚冲洗及骨水泥填充治疗的情况。方法。回顾了这14名男性和9名女性患者的记录，他们年龄在22至38岁（平均31岁）。最常受累部位是股骨远端（n = 13），其次是胫骨近端（n = 8）、股骨近端（n = 1）和胫骨远端（n = 1）。病变分为I级（n = 3）、II级（n = 18）和III级（n = 2）。根据组织学，肿瘤分期分为I级（n = 5）和II级（n = 18）。其中2例患者复发，最初分别接受了股骨远端和胫骨远端的单纯刮除及骨移植治疗。结果。平均随访期为5.7年（范围2.5 - 10.1年）。23例患者中有14例随访超过10年。无患者出现任何局部复发、远处转移或与手术或辅助治疗相关的并发症。结论。刮除、电灼、磨钻、苯酚冲洗及骨水泥填充的联合治疗对骨巨细胞瘤有效。
