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颊黏膜丝虫病:诊断难题。

Filariasis of the buccal mucosa: A diagnostic dilemma.

作者信息

Kurup Seema, Veeraraghavan Ravi, Jose Renju, Puthalath Ushass

机构信息

Department of Oral Medicine and Radiology, Amrita School of Dentistry, Kochi, Kerala, India.

出版信息

Contemp Clin Dent. 2013 Apr;4(2):254-7. doi: 10.4103/0976-237X.114883.

DOI:10.4103/0976-237X.114883
PMID:24015022
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3757895/
Abstract

Filariasis is an endemic disease in tropical and subtropical countries. Filarial nematodes can infect humans through vectors, commonly mosquitoes. Human infection can manifest as lymphatic filariasis, subcutaneous or pulmonary nodules and with eye involvement. Intra-oral presentation is very rare and often poses a diagnostic dilemma to the dentist. We report a case of intra-oral Dirofilaria repens infection in a 54-year-old female patient, involving the buccal mucosa. History was unremarkable and on clinical examination, a diffuse swelling with no significant signs and symptoms was seen. Laboratory investigations and radiographs were non-contributory to diagnosis. Ultrasound findings revealed a hypo-echoic lesion in the muscular layer of the left cheek. Differential diagnoses considered were minor salivary gland tumor, parotid sialolith, and cysticercosis among others. The presence of a Dirofilaria worm in the excised nodule confirmed the diagnosis. Medical awareness of the risk of intra-oral nematode infection is essential. A detailed travel history, awareness of endemic status of certain diseases, proper diagnosis and management helps in better prognosis for the patient.

摘要

丝虫病是热带和亚热带国家的一种地方病。丝虫线虫可通过媒介(通常是蚊子)感染人类。人类感染可表现为淋巴丝虫病、皮下或肺部结节以及眼部受累。口腔内表现非常罕见,常常给牙医带来诊断难题。我们报告一例54岁女性患者口腔内感染匐行恶丝虫的病例,累及颊黏膜。病史无异常,临床检查可见弥漫性肿胀,无明显体征和症状。实验室检查和X光片对诊断无帮助。超声检查结果显示左颊肌层有一个低回声病变。鉴别诊断考虑包括小唾液腺肿瘤、腮腺涎石、囊尾蚴病等。切除的结节中存在恶丝虫确诊了诊断。提高对口腔内线虫感染风险的医学认识至关重要。详细的旅行史、对某些疾病地方病状况的认识、正确的诊断和管理有助于患者获得更好的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b4f/3757895/95ab442912cf/CCD-4-254-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b4f/3757895/2c10e3926a29/CCD-4-254-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b4f/3757895/97ab6cf91c18/CCD-4-254-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b4f/3757895/99a090b3ed1d/CCD-4-254-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b4f/3757895/872ff6f4d00b/CCD-4-254-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b4f/3757895/95ab442912cf/CCD-4-254-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b4f/3757895/2c10e3926a29/CCD-4-254-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b4f/3757895/97ab6cf91c18/CCD-4-254-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b4f/3757895/99a090b3ed1d/CCD-4-254-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b4f/3757895/872ff6f4d00b/CCD-4-254-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b4f/3757895/95ab442912cf/CCD-4-254-g005.jpg

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本文引用的文献

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Am J Trop Med Hyg. 2008 Nov;79(5):739-41.
2
Detection of Dirofilaria (Nochtiella) repens DNA by polymerase chain reaction in embedded paraffin tissues from two human pulmonary locations.通过聚合酶链反应在来自人类肺部两个部位的石蜡包埋组织中检测匐行恶丝虫(诺氏恶丝虫)DNA
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Subtenons infection by Dirofilaria repens.匐行恶丝虫引起的眼球筋膜下感染。
J Maxillofac Oral Surg. 2019 Jun;18(2):180-189. doi: 10.1007/s12663-018-1139-7. Epub 2018 Aug 2.
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Human oral dirofilariasis.人类口腔丝虫病
Trop Parasitol. 2018 Jul-Dec;8(2):110-113. doi: 10.4103/tp.TP_49_18. Epub 2018 Dec 27.
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Intra-oral Dirofilaria repens infection: report of seven cases.口腔内匐行恶丝虫感染:7例报告
J Oral Pathol Med. 2003 Sep;32(8):502-5. doi: 10.1034/j.1600-0714.2003.00183.x.
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Ivermectin and filariasis.伊维菌素与丝虫病
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The pharmacokinetics, safety and tolerability of the co-administration of diethylcarbamazine and albendazole.乙胺嗪与阿苯达唑联合使用的药代动力学、安全性及耐受性
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Human dirofilariasis caused by Dirofilaria (Nochtiella) repens in Sri Lanka.斯里兰卡由匐行恶丝虫(诺氏恶丝虫属)引起的人体恶丝虫病。
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