Haleem S, Ansari M M, Shakoor A, Bano S
Department of Anaesthesiology, J.N. Medical College, Aligarh.
Indian J Med Res. 1990 Jun;92:192-4.
Changes in serum calcium after diethyl-ether anaesthesia given for various routine surgical operations, were studied in 30 patients. Mean (+/- SD) concentration (mg%) of serum calcium before induction of anaesthesia was 10.37 +/- 0.77. Serum calcium decreased by 0.05 per cent after 10 min of induction and by 3.33 per cent at the end of anaesthesia which was highly significant (P less than 0.001). There was a correlation (r = 0.63; P less than 0.01) between decline in serum calcium and duration of ether anaesthesia. Serum calcium returned to near normal levels after 24 h of ether anaesthesia. In view of the fall in serum calcium, it is emphasized that ether should be either avoided in patients with known or suspected hypocalcaemia or be used for as short a time as possible with due precaution and calcium supplementation.
对30例接受各种常规外科手术的患者，研究了给予乙醚麻醉后血清钙的变化。麻醉诱导前血清钙的平均（±标准差）浓度（mg%）为10.37±0.77。诱导10分钟后血清钙下降0.05%，麻醉结束时下降3.33%，差异极显著（P<0.001）。血清钙下降与乙醚麻醉持续时间之间存在相关性（r = 0.63；P<0.01）。乙醚麻醉24小时后血清钙恢复到接近正常水平。鉴于血清钙下降，强调对于已知或疑似低钙血症患者应避免使用乙醚，或在采取适当预防措施并补充钙剂的情况下尽可能缩短使用时间。
