Alon E, Caluori R, Bernoulli L, Axhausen C, Hossli G
Anaesthesist. 1982 Apr;31(4):185-7.
In catastrophe situations ether is an important alternative to the usual anaesthetics being easy to manage and economical. We wanted to study the effects of the new antiemetic Domperidone on vomiting after either anesthesia. Two groups of patients were anaesthetized for general surgical procedures by means of the EMO (Epstein-Macintosh-Oxford) Vaporizer. Half an hour before the end of the operation one group received 0.2 mg/kg domperidone while the randomized control group received no prophylactic antiemetic medication. The domperidone group showed better, statistically significant, results (p less than 0.05). Domperidone proved to have a good prophylactic antiemetic effect which does not cause side effects or circulatory alterations. In preparation for catastrophe situations ether anesthesia under improved conditions was again included in the regular training programme.
在灾难情况下，乙醚是常用麻醉剂的重要替代品，易于管理且经济实惠。我们想研究新型止吐药多潘立酮对麻醉后呕吐的影响。两组患者通过EMO（爱泼斯坦-麦金托什-牛津）蒸发器接受全身外科手术麻醉。手术结束前半小时，一组患者接受0.2mg/kg多潘立酮，而随机对照组未接受预防性止吐药物。多潘立酮组显示出更好的、具有统计学意义的结果（p小于0.05）。多潘立酮被证明具有良好的预防性止吐作用，且不会引起副作用或循环系统改变。为应对灾难情况做准备，在常规培训项目中再次纳入了条件改善后的乙醚麻醉。
