Tallner A, Mäurer M, Pfeifer K
Institut für Sportwissenschaft und Sport, Friedrich-Alexander-Universität Erlangen-Nürnberg, Gebbertstr. 123b, 91058, Erlangen, Deutschland,
Nervenarzt. 2013 Oct;84(10):1238-44. doi: 10.1007/s00115-013-3838-0.
Uncertainties concerning the pathology of multiple sclerosis have in the past led to numerous theories about the cause and therapy of the disease. In the last 40 years technological progress and the use of scientific research methods have contributed to a considerably enlarged body of medical and scientific knowledge, a process that has not yet come to an end. The attitude towards physical activity has also changed tremendously over time. There was a paradigm shift from the fear of triggering and aggravating the disease towards therapeutic benefits of physical activity and exercise. The first evidence for beneficial effects of exercise on symptoms and the course of the disease originated in the 1960s; however, a growing scientific interest in the topic was not recognizable until the 1990s when the number of exercise studies finally started to increase. Nowadays, the positive effects of physical activity and exercise are well established; nevertheless, high-quality research reports are still lacking. As a consequence there are still many unresolved questions concerning specific training effects and recommendations.
过去，关于多发性硬化症病理学的不确定性引发了众多关于该疾病病因和治疗方法的理论。在过去40年里，技术进步和科研方法的运用使医学和科学知识大幅扩充，这一过程至今仍未结束。随着时间推移，人们对体育活动的态度也发生了巨大变化。从担心引发和加重疾病，到认识到体育活动和锻炼具有治疗益处，这是一种范式转变。运动对症状和疾病进程有益的首个证据出现在20世纪60年代；然而，直到20世纪90年代运动研究数量最终开始增加时，才出现对该主题日益浓厚的科学兴趣。如今，体育活动和锻炼的积极作用已得到充分证实；尽管如此，高质量的研究报告仍然匮乏。因此，关于特定训练效果和建议仍有许多未解决的问题。
