可编程水凝胶通过 DNA 杂交的可逆性控制治疗性核酸适体的释放。
Programmable hydrogels for the controlled release of therapeutic nucleic acid aptamers via reversible DNA hybridization.
机构信息
Department of Bioengineering, College of Engineering, The Pennsylvania State University, University Park, PA 16802-6804, USA.
出版信息
Chem Commun (Camb). 2013 Oct 25;49(83):9600-2. doi: 10.1039/c3cc45594g.
PMID:24018965
Abstract
Reversible DNA hybridization can be used as a new mechanism to control the sustained and triggered release of therapeutic oligonucleotides from hydrogels.
摘要
DNA 复性杂交可作为一种新机制，用于控制治疗性寡核苷酸从水凝胶中的持续和触发释放。
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