用于控制释放纳米器件的适体薄膜结构变化的表征。
Characterization of structural changes in aptamer films for controlled release nanodevices.
机构信息
EMaS, Department of Electronic, Electric and Automation Engineering, University Rovira i Virgili, Avda. Països Catalans 26, 43007 Tarragona, Spain.
出版信息
Chem Commun (Camb). 2012 Oct 18;48(81):10087-9. doi: 10.1039/c2cc35683j.
PMID:22948231
Abstract
The dimension of the conformational changes of DNA-aptamers which can be used as stimulus-responsive gate-keepers in controlled delivery nanodevices has been determined by acoustic wave-based sensors upon molecular recognition of a small-sized target, adenosine-5'-monophosphate (AMP).
摘要
声波传感器基于对小型靶标 5'-单磷酸腺苷（AMP）的分子识别，测定了 DNA 适体构象变化的维度，这种构象变化可用作控制释放纳米器件中的刺激响应式门禁。
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