Liu Xiang, Wang Guoxin, Ge Nan, Wang Sheng, Guo Jintao, Liu Wen, Sun Siyu
1Shengjing Hospital, China Medical University, Shenyang, China.
Surg Innov. 2013 Dec;20(6):NP40-6. doi: 10.1177/1553350613499453. Epub 2013 Sep 9.
The aim of this study was to evaluate the efficacy and safety of endoscopic removal of symptomatic gastric heterotopic pancreas (HP).
From January 2010 to December 2011, 9 patients with suspected symptomatic HP were enrolled in the study. Endoscopic ultrasonography was performed to clarify the HP tissue location and to choose the endoscopic resection method. Endoscopic mucosal resection or endoscopic submucosal dissection was performed to remove the HP tissue. Symptoms in the enrolled patients were assessed before and after endoscopic removal of the HP tissue. Tumor pathology and complications were recorded after the treatment. A standard follow-up was scheduled at 1 week and 2 months after treatment.
Removal of suspected HP with endoscopic mucosal resection or endoscopic submucosal dissection was successful in all 9 cases. Abdominal pain, leukocytosis, and bleeding occurred in 6 patients, 2 patients, and 1 patient, respectively, after treatment and were relieved by symptomatic treatment. There were no other unpredictable complications. The symptoms related to HP, including epigastric pain, bloating, and postprandial fullness, were relieved significantly after the treatment. During follow-up, there was no recurrence of HP in any patient.
Endoscopic removal appears to be a safe and effective method to treat gastric lesions suspected to be HP with symptoms. The symptoms, such as epigastric pain, bloating, and postprandial fullness were well resolved after endoscopic treatment.
本研究旨在评估内镜下切除有症状的胃异位胰腺（HP）的疗效和安全性。
2010年1月至2011年12月，9例疑似有症状的HP患者纳入本研究。行内镜超声检查以明确HP组织位置并选择内镜切除方法。采用内镜黏膜切除术或内镜黏膜下剥离术切除HP组织。在HP组织内镜切除前后评估纳入患者的症状。治疗后记录肿瘤病理及并发症情况。治疗后1周和2个月安排标准随访。
9例患者均成功通过内镜黏膜切除术或内镜黏膜下剥离术切除疑似HP。治疗后分别有6例、2例和1例患者出现腹痛、白细胞增多和出血，经对症治疗后缓解。无其他不可预测的并发症。与HP相关的症状，包括上腹部疼痛、腹胀和餐后饱胀感，治疗后明显缓解。随访期间，所有患者均未出现HP复发。
内镜切除似乎是治疗疑似有症状的HP胃病变的一种安全有效的方法。内镜治疗后，上腹部疼痛、腹胀和餐后饱胀感等症状得到很好的缓解。
