Gokhale Shefali M, Lokare Sd, Nemade Pankaj
Department of Nuclear Medicine, Inlaks and Budhrani Hospital, Pune, India.
Indian J Nucl Med. 2012 Oct;27(4):231-6. doi: 10.4103/0972-3919.115393.
This study is aimed to evaluate the role of cholescintigraphy in management of acute acalculous cholecystitis.
A total of thirty two patients who had presented to the surgical out-patient department or referred from in-patient department or intensive care unit between February 2008 and February 2010 were studied. All patients with Ultrasonography abdomen findings of acalculous cholecystitis were included in the study and they underwent cholescintigraphy. Gall bladder ejection fraction (GBEF) was calculated 30 min after fatty meal. Patients who either had non-visualization of gall bladder or GBEF less than 40% were considered to have acalculous cholecystitis on cholescintigraphy. The patients were followed-up for a period of 3 months after the commencement of treatment.
Eleven patients had either non-visualization of gall bladder or GBEF < 40%. Of these, six patients underwent cholecystectomy and the rest were medically managed, as patients deferred surgery. 83.33% of post-cholecystectomy patients as against 40% of medically treated patients were symptom free. Twenty one patients had GBEF > 40%, 90.74% of these patients were symptom free at the end of 3 months, with medical management.
Cholescintigraphy is an important adjunct in management of patients with acalculous cholecystitis by guiding the course of therapy-surgical management versus medical management.
本研究旨在评估胆囊闪烁扫描术在急性非结石性胆囊炎治疗中的作用。
对2008年2月至2010年2月期间到外科门诊就诊或从住院部或重症监护病房转诊的32例患者进行了研究。所有腹部超声检查发现非结石性胆囊炎的患者均纳入本研究,并接受了胆囊闪烁扫描术。在进食脂肪餐后30分钟计算胆囊射血分数(GBEF)。胆囊未显影或GBEF低于40%的患者在胆囊闪烁扫描术中被视为患有非结石性胆囊炎。患者在开始治疗后随访3个月。
11例患者胆囊未显影或GBEF<40%。其中,6例患者接受了胆囊切除术,其余患者因推迟手术而接受药物治疗。胆囊切除术后患者的无症状率为83.33%,而药物治疗患者的无症状率为40%。21例患者GBEF>40%,在药物治疗3个月结束时,这些患者中有90.74%无症状。
胆囊闪烁扫描术通过指导治疗方案(手术治疗与药物治疗)的选择,在急性非结石性胆囊炎患者的治疗中是一项重要的辅助手段。