微刺激方案：一种廉价且有效的促排卵方法。
Minimal stimulation protocol: a cheap and effective method of ovulation induction.
作者信息
Mathew M, Al-Busaidi F, Krolikowski A
机构信息
Department of Obstetrics & Gynaecology, Sultan Qaboos University, P O Box 35 Al-Khod, Muscat 123, Sultanate of Oman.
出版信息
J Sci Res Med Sci. 2000 Jan;2(1):33-5.
OBJECTIVE
To determine the effectiveness and cost of Minimal Stimulation Protocol (MSP), a new combination of human menopausal gonadotrophin (hMG) and clomiphene citrate (CC), for controlled ovarian hyperstimulation.
METHOD
The ovulation rates, pregnancy rates, abortion rates and the cost of medication were assessed in respect of 67 women who underwent MSP.
RESULTS
Ovulation rate in the study group was 82%, pregnancy rate 21% and multiple pregnancies 7%. Spontaneous abortion occurred in 36% of the pregnancies. The average cost of MSP stimulation was one-third of hMG protocol.
CONCLUSION
MSP protocol, while substantially cheaper than hMG, gives comparable pregnancy rates with less need for monitoring and better patient comfort. These justify further evaluation of its role in the treatment of infertility.
目的
确定一种新的人绝经期促性腺激素（hMG）与枸橼酸氯米芬（CC）联合应用的微刺激方案（MSP）用于控制性卵巢过度刺激的有效性和成本。
方法
对67例接受MSP的女性的排卵率、妊娠率、流产率及药物成本进行评估。
结果
研究组排卵率为82%，妊娠率为21%，多胎妊娠率为7%。36%的妊娠发生自然流产。MSP刺激的平均成本是hMG方案的三分之一。
结论
MSP方案虽然比hMG便宜得多，但妊娠率相当，监测需求较少，患者舒适度更高。这些都证明有必要进一步评估其在不孕症治疗中的作用。
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