Randall J M, Templeton A
Department of Obstetrics and Gynaecology, University of Aberdeen, Maternity Hospital, Scotland.
Fertil Steril. 1991 Aug;56(2):208-12. doi: 10.1016/s0015-0282(16)54473-2.
Assessment of follicular development and endometrial growth using transvaginal sonography in spontaneous and clomiphene citrate (CC) cycles with a spontaneous luteinizing hormone surge.
Prospective study of a spontaneous cycle followed by a CC cycle to compare paired data.
Institutional tertiary referral infertility clinic.
Eighteen couples with primary unexplained infertility voluntarily recruited from the infertility clinic.
Daily transvaginal sonography and endocrine monitoring. Clomiphene citrate (150 mg) was administered on days 5 to 9 of CC cycle.
Leading follicular diameter and endometrial thickness.
The growth rate of the leading follicle was similar in both study cycles, although in CC cycles the leading follicle diameter was significantly larger. Endometrial thickness was reduced in CC cycles.
Follicular development and endometrial thickness are altered in CC cycles.
在自然周期和枸橼酸氯米芬（CC）周期且黄体生成素自发峰的情况下，使用经阴道超声评估卵泡发育和子宫内膜生长情况。
对自然周期随后进行CC周期的前瞻性研究，以比较配对数据。
机构三级转诊不孕症诊所。
从不孕症诊所自愿招募的18对原发性不明原因不孕症夫妇。
每日经阴道超声检查和内分泌监测。在CC周期的第5至9天给予枸橼酸氯米芬（150毫克）。
主导卵泡直径和子宫内膜厚度。
尽管在CC周期中主导卵泡直径明显更大，但两个研究周期中主导卵泡的生长速率相似。CC周期中子宫内膜厚度降低。
CC周期中卵泡发育和子宫内膜厚度发生改变。
