Riad Hassan, Mannai Haya Al, Mansour Khalid, Qaatri Khalifa Al, Dosari Sharifa Al, Obaidaly Amina Al, Sultan Emad
Dermatology Department, Rumailah Hospital, Doha, Qatar.
Case Rep Dermatol. 2013 Aug 17;5(2):225-31. doi: 10.1159/000354767. eCollection 2013.
Alopecia areata and vitiligo are autoimmune diseases, both associated with multiple autoimmune comorbidities. Many studies show colocalization of these diseases at the same anatomical site. Here, we have a case where both disorders were reported to present in the same patient. Diphenylcyclopropenone (diphencyprone, DCP) is used in the treatment of alopecia areata and may induce vitiligo in some patients. We report on one case of vitiligo that was induced by DCP during therapy for alopecia universalis. Alopecia areata and vitiligo share many susceptibility genes. Follicular melanocyte destruction may represent the link between the two diseases.
斑秃和白癜风是自身免疫性疾病，均与多种自身免疫性合并症相关。许多研究表明这些疾病在同一解剖部位共定位。在此，我们有一例报告称这两种病症出现在同一患者身上。二苯环丙烯酮（二苯环丙醇，DCP）用于治疗斑秃，且可能在一些患者中诱发白癜风。我们报告一例在全秃治疗期间由DCP诱发的白癜风病例。斑秃和白癜风共有许多易感基因。毛囊黑素细胞破坏可能代表这两种疾病之间的联系。
