Ramot Yuval, Thomaidou Elena, Mali Alexander, Zlotogorski Abraham
Department of Dermatology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Int J Trichology. 2010 Jul;2(2):108-9. doi: 10.4103/0974-7753.77522.
Although the association of alopecia areata (AA) and vitiligo occurring in the same patient has been frequently reported in the literature, the colocalization of AA and vitiligo is very rare. We report for the first time an adult patient with anatomic concurrence of AA and vitiligo on the scalp. Even though both AA and vitiligo are thought to have the same underlying pathophysiologic mechanisms, the striking rarity of their colocalization challenges this postulated common pathogenesis, and raises the question if autoimmunity is responsible for only a fraction of AA or vitiligo.
尽管斑秃(AA)和白癜风在同一患者中并发的情况在文献中已有频繁报道,但AA和白癜风在解剖学上的共定位却非常罕见。我们首次报告了一名成年患者,其头皮上同时出现了AA和白癜风。尽管人们认为AA和白癜风具有相同的潜在病理生理机制,但它们共定位现象极为罕见,这对这种假定的共同发病机制提出了挑战,并引发了自身免疫是否仅导致部分AA或白癜风病例的疑问。