Fiebig Anne, Pradella Silke, Petersen Jörn, Päuker Orsola, Michael Victoria, Lünsdorf Heinrich, Göker Markus, Klenk Hans-Peter, Wagner-Döbler Irene
Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany.
Stand Genomic Sci. 2013 Feb 25;7(3):413-26. doi: 10.4056/sigs.3456959. eCollection 2013.
Labrenzia alexandrii Biebl et al. 2007 is a marine member of the family Rhodobacteraceae in the order Rhodobacterales, which has thus far only partially been characterized at the genome level. The bacterium is of interest because it lives in close association with the toxic dinoflagellate Alexandrium lusitanicum. Ultrastructural analysis reveals R-bodies within the bacterial cells, which are primarily known from obligate endosymbionts that trigger "killing traits" in ciliates (Paramecium spp.). Genomic traits of L. alexandrii DFL-11(T) are in accordance with these findings, as they include the reb genes putatively involved in R-body synthesis. Analysis of the two extrachromosomal elements suggests a role in heavy-metal resistance and exopolysaccharide formation, respectively. The 5,461,856 bp long genome with its 5,071 protein-coding and 73 RNA genes consists of one chromosome and two plasmids, and has been sequenced in the context of the Marine Microbial Initiative.
亚历山大拉布伦齐亚菌（Labrenzia alexandrii）比布尔等人于2007年发现，它是红杆菌目（Rhodobacterales）红杆菌科（Rhodobacteraceae）的海洋成员，迄今为止仅在基因组水平上得到部分表征。这种细菌备受关注，因为它与有毒的腰鞭毛虫——葡萄牙亚历山大藻（Alexandrium lusitanicum）密切共生。超微结构分析显示，细菌细胞内存在R体，R体主要存在于专性内共生体中，这些内共生体会在纤毛虫（草履虫属，Paramecium spp.）中引发“杀伤特性”。亚历山大拉布伦齐亚菌DFL-11(T)的基因组特征与这些发现相符，因为其中包括可能参与R体合成的reb基因。对两个染色体外元件的分析表明，它们分别在重金属抗性和胞外多糖形成中发挥作用。这个长度为5,461,856 bp的基因组，包含5,071个蛋白质编码基因和73个RNA基因，由一条染色体和两个质粒组成，是在海洋微生物计划的背景下进行测序的。
