Graduate Institute of Behavioral Sciences, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan.
Res Dev Disabil. 2013 Nov;34(11):3709-19. doi: 10.1016/j.ridd.2013.07.025. Epub 2013 Sep 7.
We investigated the three parameters (mu, sigma, tau) of ex-Gaussian distribution of RT derived from the Conners' continuous performance test (CCPT) and examined the moderating effects of the energetic factors (the inter-stimulus intervals (ISIs) and Blocks) among these three parameters, especially tau, an index describing the positive skew of RT distribution. We assessed 195 adolescents with DSM-IV ADHD, and 90 typically developing (TD) adolescents, aged 10-16. Participants and their parents received psychiatric interviews to confirm the diagnosis of ADHD and other psychiatric disorders. Participants also received intelligence (WISC-III) and CCPT assessments. We found that participants with ADHD had a smaller mu, and larger tau. As the ISI/Block increased, the magnitude of group difference in tau increased. Among the three ex-Gaussian parameters, tau was positively associated with omission errors, and mu was negatively associated with commission errors. The moderating effects of ISIs and Blocks on tau parameters suggested that the ex-Gaussian parameters could offer more information about the attention state in vigilance task, especially in ADHD.
我们研究了康纳斯持续操作测验（CCPT）中 RT 的外伽马分布的三个参数（mu、sigma、tau），并考察了这些参数（尤其是 tau，它是描述 RT 分布正偏度的指标）之间的能量因素（刺激间间隔（ISIs）和块）的调节作用。我们评估了 195 名符合 DSM-IV ADHD 标准的青少年和 90 名典型发展（TD）青少年，年龄在 10-16 岁之间。参与者及其父母接受了精神病学访谈，以确认 ADHD 和其他精神障碍的诊断。参与者还接受了智力（WISC-III）和 CCPT 评估。我们发现 ADHD 患者的 mu 值较小，tau 值较大。随着 ISI/Block 的增加，tau 上的组间差异的幅度增加。在外伽马参数中，tau 与遗漏错误呈正相关，mu 与错误呈负相关。ISIs 和 Blocks 对 tau 参数的调节作用表明，外伽马参数可以提供更多关于警觉任务中注意力状态的信息，尤其是在 ADHD 中。
