Cobb N, Slater D N, Beck S
Dept of Histopathology, Rotherham District General Hospital, England, UK.
Med Lab Sci. 1990 Jul;47(3):172-81.
We describe a new filtration method based on a transport medium technique which allows histopathological assessment of the tissue fragments present in many fine needle aspirates. Fine needle aspiration cytology and biopsy preparations obtained from equally divided transport medium specimens were compared in a study comprising 104 palpable breast lesions and 29 other miscellaneous lesions. In general, fine needle aspiration biopsy provided better information on tumour origin and differentiation than fine needle aspiration cytology, particularly with systemic aspirates and those which were heavily bloodstained. In most instances fine needle aspiration biopsy also provided sufficient material to perform specialised staining and immunohistological techniques, and it is suggested that it may have a role in supplementing direct smear fine needle aspiration cytology in these areas.
我们描述了一种基于转运介质技术的新过滤方法，该方法可对许多细针穿刺抽吸物中的组织碎片进行组织病理学评估。在一项包含104例可触及乳腺病变和29例其他杂类病变的研究中，对从等量转运介质标本中获得的细针穿刺细胞学和活检标本进行了比较。总体而言，细针穿刺活检在肿瘤起源和分化方面比细针穿刺细胞学提供了更好的信息，特别是对于系统性抽吸物和那些严重血染的标本。在大多数情况下，细针穿刺活检也提供了足够的材料来进行特殊染色和免疫组织学技术，并且有人提出，在这些领域它可能在补充直接涂片细针穿刺细胞学方面发挥作用。
