Maturana M, Contreras L
Departamento de Cirugía, Facultad de Medicina, Universidad de Chile, Santiago.
Rev Med Chil. 1993 Dec;121(12):1395-403.
A new methodology to obtain tissue samples from breast tumors through fine needle aspiration is described. This consists of a screwdriver like movement of the needle and continuous aspiration. The tissue is embedded in a blood clot, fixed in 10% formalin and routinely processed for histopathological study. From March 1987 to March 1990 this technique was applied in 84 patients. Ten did not have conventional histopathological study. The 74 patients studied had 76 tumors. Six cases (7.9%) had "unsatisfactory" specimens and nine (11.8%) only allowed cytological diagnosis. The 61 remaining samples (80.3%) were considered "sufficient" for histopathological study. The new methodology had a sensitivity of 95.5% specificity of 100% and positive predictive value of 100%. In this series there were no false positive cases.
本文描述了一种通过细针穿刺从乳腺肿瘤获取组织样本的新方法。该方法包括类似螺丝刀转动的进针动作和持续抽吸。组织被包埋在血凝块中，用10%福尔马林固定，然后常规处理用于组织病理学研究。从1987年3月至1990年3月，该技术应用于84例患者。其中10例未进行常规组织病理学研究。接受研究的74例患者有76个肿瘤。6例（7.9%）样本“不满意”，9例（11.8%）仅能进行细胞学诊断。其余61个样本（80.3%）被认为足以进行组织病理学研究。新方法的敏感性为95.5%，特异性为100%，阳性预测值为100%。在该系列中无假阳性病例。
