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[关于发病机制的犬缺血后水肿中的蛋白质分布(作者译)]

[The protein distribution in the postischemic edema of dogs in reference to pathogenesis (author's transl)].

作者信息

Stock W, Hermann G, Welter H

出版信息

Thoraxchir Vask Chir. 1975 Jun;23(3):265-70. doi: 10.1055/s-0028-1096961.

Abstract

A postischemic edema in hind limbs of dogs occurred after a 5 hours tourniquet ischemia. The protein distribution of edematous liquid, serum and lymph has been investigated by immunoelectrophoretic analysis. Using different identification reactions it could be demonstrated, that edematous liquid only differs from serum because of additional appearance of fibrinogen, so corresponding qualitatively and in so far estimated quantitatively to serum plasma. In connection with the osmotic pressure factors and postischemic hyperemia, as they have been demonstrated up to now, the severe changes of permeability seem to be a main factor in pathogenesis of postischemic edemas.

摘要

狗后肢在经历5小时止血带缺血后出现缺血后水肿。通过免疫电泳分析研究了水肿液、血清和淋巴中的蛋白质分布。利用不同的鉴定反应可以证明,水肿液与血清的不同仅在于纤维蛋白原的额外出现,因此在质量上与血清血浆相对应,并且在一定程度上可以进行定量估计。结合目前已证实的渗透压因素和缺血后充血情况,通透性的严重改变似乎是缺血后水肿发病机制中的一个主要因素。

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