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眼眶孤立性纤维瘤伴多发性腔隙。

Solitary fibrous tumor of the orbit with multiple cavities.

机构信息

Department of Ophthalmology, University of North Carolina, Chapel Hill, North Carolina, U.S.A.

出版信息

Ophthalmic Plast Reconstr Surg. 2013 Sep-Oct;29(5):e117-9. doi: 10.1097/IOP.0b013e318279fdd6.

Abstract

Solitary fibrous tumors (SFTs) are rare spindle cell neoplasms of mesenchymal origin that most commonly arise within pleura and have also been reported in many extrapleural sites including the orbit. Cavitary changes within SFT of both pleura and extrapleural sites have been documented, but remain very rare. To the authors' knowledge, the third known case of an orbital solitary fibrous tumor containing large pseudocystic cavities is described. MRI demonstrated a heterogeneous enhancing mass with multiple cavities. Excisional biopsy revealed solid tumor with large cavities filled with straw-colored fluid and tumor cells that stained positive for CD34 and CD99 antigens, consistent with SFT. The patient had an uncomplicated postoperative course with no sign of recurrence and resolution of the proptosis after 12 months of follow up. SFT are rare benign orbital neoplasms that rarely present with cavitary changes. Current treatment options include complete surgical excision, which was performed in this case. Close follow up is advised to monitor for recurrence.

摘要

孤立性纤维瘤(SFT)是一种罕见的间叶来源的梭形细胞肿瘤,最常见于胸膜内,也有许多胸膜外部位的报道,包括眼眶。已经记录了胸膜和胸膜外部位 SFT 中的空洞性改变,但仍然非常罕见。据作者所知,描述了第三个眼眶孤立性纤维瘤包含大假囊性腔的已知病例。MRI 显示不均匀增强肿块伴多个腔。切除活检显示实性肿瘤,有大腔充满稻草色液体和肿瘤细胞,CD34 和 CD99 抗原染色阳性,符合 SFT。患者术后无并发症,无复发迹象,随访 12 个月后眼球突出缓解。SFT 是罕见的良性眼眶肿瘤,很少出现空洞性改变。目前的治疗选择包括完全手术切除,本例中即采用了该方法。建议密切随访以监测复发。

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