Filler Guido, Clark William F, Huang Shih-Han S
Department of Pediatrics, Division of Nephrology, Children's Hospital, London Health Science Centre-University of Western Ontario, 800 Commissioners Road East, London, ON, Canada, N6A 5W9,
Pediatr Nephrol. 2014 Nov;29(11):2077-82. doi: 10.1007/s00467-013-2620-7. Epub 2013 Sep 11.
The combination of hemodialysis and plasma exchange as one tandem procedure was first described in 1999 by Siami et al. (ASAIO J 45:229-233), but larger pediatric case series were not described until 2012. Even in adults, there are only limited case series. If performed in sequence, up to 8 h of treatment time may be required. With the use of the tandem procedure in stable patients, the same procedures can be completed during the same time as a routine hemodialysis, which is more convenient for patients and may reduce healthcare costs. Little is known about the utilization of the combination of hemodialysis and plasma exchange in children. The purpose of this review is to summarize the adult and scarce pediatric experience. The results of a survey carried out by the authors using the Internet listserver "PedNeph" to obtain an overview of the current practice patterns of pediatric nephrologists are also presented.
血液透析和血浆置换联合作为一种串联程序，最早于1999年由西亚米等人描述（《美国人工脏器学会杂志》45:229 - 233），但直到2012年才出现更大规模的儿科病例系列报道。即便在成人中，病例系列也很有限。若按顺序进行，可能需要长达8小时的治疗时间。在稳定患者中使用串联程序时，相同的程序可在与常规血液透析相同的时间内完成这对患者来说更方便，且可能降低医疗成本。关于儿童血液透析和血浆置换联合应用的情况知之甚少。本综述的目的是总结成人及稀缺的儿科经验。还展示了作者利用互联网列表服务器“PedNeph”进行的一项调查结果，以了解儿科肾病学家当前的实践模式概况。
