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巨细胞病毒诱导的结肠狭窄在免疫功能正常的成年人中表现为急性肠梗阻。

Cytomegalovirus-induced colonic stricture presenting as acute intestinal obstruction in an immunocompetent adult.

作者信息

Dinesh B V, Selvaraju Karthikeyan, Kumar Sampath, Thota Sumath

机构信息

Department of General Surgery, Kasturba Medical College, Manipal, Karnataka, India.

出版信息

BMJ Case Rep. 2013 Sep 10;2013:bcr-2013-200944. doi: 10.1136/bcr-2013-200944.

DOI:10.1136/bcr-2013-200944
PMID:24022906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3794276/
Abstract

Cytomegalovirus (CMV) infection causes significant morbidty and mortality in immunopromised patients. Though it is usually silent in immunocompetent adults, rarely it can cause serious life-threatening complications. Gastrointestinal tract is one of the commonly involved organs, where it produces a spectrum of clinical manifestation ranging from mild non-specific abdominal pain and diarrhoea to severe infection with toxic megacolon and death. We present a 65-year-old immunocompetent male patient admitted with acute colonic obstruction secondary to CMV-induced colonic stricture, highlighting the importance of considering it as a differential diagnosis for colonic obstruction and reviewing its management.

摘要

巨细胞病毒(CMV)感染在免疫功能低下的患者中会导致严重的发病和死亡。虽然它在免疫功能正常的成年人中通常无症状,但极少数情况下会引发严重的危及生命的并发症。胃肠道是常见受累器官之一,其临床表现多样,从轻微的非特异性腹痛和腹泻到严重感染导致中毒性巨结肠甚至死亡。我们报告了一名65岁免疫功能正常的男性患者,因CMV诱导的结肠狭窄继发急性结肠梗阻入院,强调了将其作为结肠梗阻鉴别诊断及回顾其治疗方法的重要性。

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Cytomegalovirus oesophagitis following treatment with fludarabine for refractory lymphoplasmacytic lymphoma.氟达拉滨治疗难治性淋巴浆细胞淋巴瘤后发生的巨细胞病毒食管炎。
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Cytomegalovirus colitis in immunocompetent patients.免疫功能正常患者的巨细胞病毒性结肠炎。
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Cytomegalovirus ileitis in an immunocompetent patient.免疫功能正常患者的巨细胞病毒性回肠炎。
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Recurrent cytomegalovirus colitis with megacolon in an immunocompetent elderly man.免疫功能正常的老年男性反复发生巨结肠的巨细胞病毒性结肠炎。
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Cytomegalovirus associated colonic pseudotumor: a consequence of iatrogenic immunosuppression in a patient with primary brain tumor receiving radiation and temozolomide.巨细胞病毒相关的结肠假瘤:一名接受放疗和替莫唑胺治疗的原发性脑肿瘤患者医源性免疫抑制的后果。
J Neurooncol. 2009 Sep;94(3):445-8. doi: 10.1007/s11060-009-9882-8. Epub 2009 Apr 10.
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Immunobiology of human cytomegalovirus: from bench to bedside.人类巨细胞病毒的免疫生物学:从 bench 到 bedside。 (注:bench 与 bedside 在这里可能是一种形象说法,bench 可理解为基础研究阶段,bedside 可理解为临床应用阶段,直译为“从实验台到病床边”,意译为“从基础研究到临床应用” ) 准确完整的译文:人类巨细胞病毒的免疫生物学:从基础研究到临床应用
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