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Primary and secondary prevention of cardiovascular disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.心血管疾病的一级和二级预防:抗血栓治疗和血栓预防,第 9 版:美国胸科医师学院基于证据的临床实践指南。
Chest. 2012 Feb;141(2 Suppl):e637S-e668S. doi: 10.1378/chest.11-2306.
2
A Case of Distal Embolization of Left Ventricular Thrombus due to Blunt Chest Trauma-Induced Coronary Artery Occlusion.钝性胸部创伤致冠状动脉闭塞导致左心室血栓远端栓塞 1 例
Korean Circ J. 2011 Aug;41(8):486-9. doi: 10.4070/kcj.2011.41.8.486. Epub 2011 Aug 31.
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Traumatic coronary artery dissection: a case report and literature review.创伤性冠状动脉夹层:一例病例报告及文献综述
J Emerg Med. 2012 Oct;43(4):e239-43. doi: 10.1016/j.jemermed.2010.04.019. Epub 2010 Jun 7.
4
Acute myocardial infarction due to left anterior descending coronary artery dissection after blunt chest trauma.钝性胸部创伤后左前降支冠状动脉夹层导致的急性心肌梗死
Emerg Radiol. 2010 Mar;17(2):149-51. doi: 10.1007/s10140-009-0799-5. Epub 2009 Feb 13.
5
Extensive myocardial infarction and left ventricular thrombus after chest collision during a soccer match.足球比赛中胸部碰撞后发生广泛心肌梗死及左心室血栓形成
Clin Cardiol. 2006 Dec;29(12):547-8. doi: 10.1002/clc.20029.
6
Prior blunt chest trauma may be a cause of single vessel coronary disease; hypothesis and review.既往钝性胸部创伤可能是单支血管冠状动脉疾病的一个病因;假说与综述。
Int J Cardiol. 2006 Mar 22;108(1):1-5. doi: 10.1016/j.ijcard.2005.04.010. Epub 2005 Jun 17.
7
Spontaneous coronary artery dissection following low-intensity blunt chest trauma: a case report and review of current treatment options.低强度钝性胸部创伤后自发性冠状动脉夹层:一例报告及当前治疗选择的综述
J Invasive Cardiol. 2002 Nov;14(11):679-81.
8
Intravascular ultrasound assessment of spontaneous coronary artery dissection.自发性冠状动脉夹层的血管内超声评估
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9
Acute anterior myocardial infarction following a mild nonpenetrating chest trauma--a case report.轻度非穿透性胸部创伤后急性前壁心肌梗死——病例报告
Angiology. 2001 Apr;52(4):279-82. doi: 10.1177/000331970105200408.
10
Cardiac contusion in blunt chest trauma: a combined study of transesophageal echocardiography and cardiac troponin I determination.钝性胸部创伤中的心脏挫伤:经食管超声心动图与心肌肌钙蛋白I测定的联合研究
Ital Heart J. 2001 Mar;2(3):222-7.

远隔部位钝性胸部创伤后的心源性栓塞性卒中

Cardio-embolic stroke following remote blunt chest trauma.

作者信息

Arora Sonali, Atreya Auras R, Penumetsa Srikanth C, Hiser William L

机构信息

Department of Internal Medicine, Baystate Medical Center/Tufts University School of Medicine, Springfield, MA, USA.

出版信息

J Cardiovasc Dis Res. 2013 Mar;4(1):61-4. doi: 10.1016/j.jcdr.2013.02.007. Epub 2013 Mar 6.

DOI:10.1016/j.jcdr.2013.02.007
PMID:24023477
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3758092/
Abstract

A cardio-embolic stroke as a sequela of remote blunt chest trauma is a rare clinical presentation. Blunt chest trauma can cause various acute cardiac complications like arrhythmias, cardiac contusion etc. However, delayed consequences such as left ventricular thrombus resulting in thromboembolic phenomena are reported infrequently. A 30-year-old healthy man presented to an outside facility with transient neurological deficits. An MRI brain showed lesions suggestive of embolic etiology. A trans-thoracic echocardiogram (TTE) showed a 1.5 × 1.5 cm mass present in the left ventricular (LV) apex. Patient was transferred to our institution for cardiac surgery evaluation. On detailed questioning, he reported an incident of blunt chest trauma during a martial arts exhibition fight that took place 2 years back. Given this history, a cardiac catheterization was done, which showed 30% stenosis in mid-left anterior descending artery (LAD) without any other significant obstructive lesion. A trans-esophageal echocardiogram (TEE) showed akinesis of the LV apex and confirmed TTE finding of a mass, consistent with an apical thrombus. Surgery was deferred and patient was started on anticoagulation. A cardiac MRI done 2 weeks later showed evidence of apical infarction in the LAD territory. LAD is the most commonly affected coronary vessel by blunt traumatic injuries, likely due to its vulnerable anatomical position on the anterior aspect of the heart. A variety of mechanisms including intimal tear, rupture and spasm have been implicated in the pathogenesis of myocardial infarction after blunt chest trauma.

摘要

作为远期钝性胸部创伤后遗症的心脏栓塞性卒中是一种罕见的临床表现。钝性胸部创伤可导致各种急性心脏并发症,如心律失常、心脏挫伤等。然而,诸如左心室血栓导致血栓栓塞现象等延迟后果的报道并不常见。一名30岁的健康男性因短暂性神经功能缺损被送往外部医疗机构。脑部MRI显示病变提示栓塞病因。经胸超声心动图(TTE)显示左心室(LV)心尖部有一个1.5×1.5 cm的肿块。患者被转至我院进行心脏手术评估。经详细询问,他报告了2年前在一次武术表演打斗中发生的钝性胸部创伤事件。鉴于此病史,进行了心脏导管插入术,结果显示左前降支(LAD)中段有30%的狭窄,无任何其他明显的阻塞性病变。经食管超声心动图(TEE)显示LV心尖部运动减弱,并证实了TTE发现的肿块,与心尖部血栓一致。手术推迟,患者开始接受抗凝治疗。2周后进行的心脏MRI显示LAD区域有心尖部梗死的证据。LAD是钝性创伤中最常受累的冠状动脉,可能是由于其在心脏前侧的易损解剖位置。钝性胸部创伤后心肌梗死的发病机制涉及多种机制,包括内膜撕裂、破裂和痉挛。