Tong De-Sheng, Liu Yi-Xin, Tang Feng
Jiangsu Institute of Parasitic Diseases, Wuxi 214064, China.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2013 Jun;25(3):327-8.
To study the detection effects of ELISA for the infections of Cysticercus, Echinococcosus, Paragonimus westermani and Sparganum mansoni in order to improve diagnosis.
The patients who admitted to Jiangsu Institute of Parasitic Diseases from 2008 to 2001 were selected as the subjects and their sera were detected for IgG against Cysticercus, Echinococcosus, and Paragonimus westermani from January 2008 to March 2011, and IgG against Sparganum mansoni since June, 2011 by ELISA.
A total of 282 cases were detected, and 88 of them were found one or two positive results, and the total positive rate was 31.2%. There were 39, 2, 21, and 3 cases of positive IgG of Cysticercus, Echinococcosus, Paragonimus westermani and Sparganum mansoni, respectively. There were 15 cases of positive IgG to both Cysticercus and Echinococcosus; there were 5 cases of positive IgG to both Cysticercus and Paragonimus westermani; there were 3 cases of positive IgG to both Echinococcosus and Paragonimus westermani. The cross reactions occurred in 23 serum samples among 88 positive samples with a cross reaction rate of 26.1%.
There still exist a certain number of patients with parasitic diseases, and the cross reaction may occur in the detection process of IgG to Cysticercus, Echinococcosus, Paragonimus westermani and Sparganum mansoni by ELISA.
研究酶联免疫吸附测定（ELISA）法对囊尾蚴、棘球蚴、卫氏并殖吸虫和曼氏裂头蚴感染的检测效果，以提高诊断水平。
选取2008年至2011年期间入住江苏省寄生虫病防治研究所的患者作为研究对象，于2008年1月至2011年3月采用ELISA法检测其血清中抗囊尾蚴、抗棘球蚴和抗卫氏并殖吸虫IgG，自2011年6月起检测抗曼氏裂头蚴IgG。
共检测282例，其中88例出现一项或两项阳性结果，总阳性率为31.2%。囊尾蚴、棘球蚴、卫氏并殖吸虫和曼氏裂头蚴IgG阳性分别为39例、2例、21例和3例。囊尾蚴和棘球蚴IgG均阳性15例；囊尾蚴和卫氏并殖吸虫IgG均阳性5例；棘球蚴和卫氏并殖吸虫IgG均阳性3例。88份阳性样本中有23份血清样本出现交叉反应，交叉反应率为26.1%。
寄生虫病患者仍有一定数量，ELISA法检测抗囊尾蚴、抗棘球蚴、抗卫氏并殖吸虫和抗曼氏裂头蚴IgG过程中可能出现交叉反应。
