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成年人的乳制品:从食物到营养素相互作用对骨骼和骨骼肌健康的影响。

Dairy in adulthood: from foods to nutrient interactions on bone and skeletal muscle health.

机构信息

a Division of Bone Disease , University Hospitals and Faculty of Medicine , Geneva , SWITZERLAND.

出版信息

J Am Coll Nutr. 2013;32(4):251-63. doi: 10.1080/07315724.2013.816604.

Abstract

The risk of fragility fractures exponentially increases with aging. Reduced mass and strength of both bone in osteoporosis and skeletal muscle in sarcopenia play a key role in the age-related incidence of fragility fractures. Undernutrition is often observed in the elderly, particularly in those subjects experiencing osteoporotic fractures, more likely as a cause than a consequence. Calcium (Ca), inorganic phosphate (Pi), vitamin D, and protein are nutrients that impact bone and skeletal muscle integrity. Deficiency in the supply of these nutrients increases with aging. Dairy foods are rich in Ca, Pi, and proteins and in many countries are fortified with vitamin D. Dairy foods are important souces of these nutrients and go a long way to meeting the recommendations, which increase with aging. This review emphaszes the interactions between these 4 nutrients, which, along with physical activity, act through cellular and physiological pathways favoring the maintenance of both bone and skeletal muscle structure and function.

摘要

随着年龄的增长,脆性骨折的风险呈指数级增加。骨质疏松症中骨量和强度的降低,以及肌肉减少症中骨骼肌肉的减少,在与年龄相关的脆性骨折发生率中起着关键作用。老年人常常存在营养不良的情况,尤其是那些经历过骨质疏松性骨折的患者,营养不良更可能是原因而不是结果。钙(Ca)、无机磷(Pi)、维生素 D 和蛋白质是影响骨骼和骨骼肌肉完整性的营养素。这些营养素的供应不足随着年龄的增长而增加。乳制品富含 Ca、Pi 和蛋白质,而且在许多国家都添加了维生素 D。乳制品是这些营养素的重要来源,并且在很大程度上满足了随着年龄增长而增加的建议。本文综述强调了这 4 种营养素之间的相互作用,这些营养素与体力活动一起,通过细胞和生理途径作用,有利于维持骨骼和骨骼肌肉的结构和功能。

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