a Monash University.
Am J Bioeth. 2013;13(10):29-38. doi: 10.1080/15265161.2013.828115.
This article discusses the ethics of the use of preimplantation genetic diagnosis (PGD) to prevent the birth of children with intersex conditions/disorders of sex development (DSDs), such as congenital adrenal hyperplasia (CAH) and androgen insensitivity syndrome (AIS). While pediatric surgeries performed on children with ambiguous genitalia have been the topic of intense bioethical controversy, there has been almost no discussion to date of the ethics of the use of PGD to reduce the prevalence of these conditions. I suggest that PGD for those conditions that involve serious medical risks for those born with them is morally permissible and that PGD for other "cosmetic" variations in sexual anatomy is more defensible than might first appear. However, importantly, the arguments that establish the latter claim have radical and disturbing implications for our attitude toward diversity more generally.
这篇文章讨论了使用胚胎植入前遗传学诊断（PGD）来预防患有间性疾病/性发育障碍（DSD）的儿童出生的伦理问题，例如先天性肾上腺增生症（CAH）和雄激素不敏感综合征（AIS）。虽然对具有两性生殖器的儿童进行的儿科手术一直是激烈的生物伦理争议的主题，但迄今为止，几乎没有讨论过使用 PGD 来降低这些疾病的发生率的伦理问题。我认为，对于那些对患有这些疾病的人存在严重医疗风险的疾病，使用 PGD 是符合道德规范的，而对于其他“美容”性生殖器解剖结构的变化，PGD 的使用则比最初看起来更有说服力。然而，重要的是，支持后一种说法的论点对我们更普遍地对待多样性的态度产生了激进和令人不安的影响。
