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欧美植入前基因诊断政策比较及其对生殖旅游的影响

Comparative preimplantation genetic diagnosis policy in Europe and the USA and its implications for reproductive tourism.

作者信息

Bayefsky Michelle J

机构信息

Bioethics Department, National Institutes of Health, 10 Center Drive, Building 10, Room 1C118, Bethesda, Maryland, USA 20892,

出版信息

Reprod Biomed Soc Online. 2016 Dec;3:41-47. doi: 10.1016/j.rbms.2017.01.001.

Abstract

Unlike many European nations, the USA has no regulations concerning the use of preimplantation genetic diagnosis (PGD), a technique employed during some fertility treatments to select embryos based on their genes. As such, PGD can and is used for a variety of controversial purposes, including sex selection, selection for children with disabilities such as deafness, and selection for 'saviour siblings' who can serve as tissue donors for sick relatives. The lack of regulation, which is due to particular features of the US political and economic landscape, has ethical and practical implications for patients seeking PGD around the world. This paper contrasts the absence of PGD oversight in the USA with existing PGD policies in Switzerland, Italy, France and the UK. The primary reasons why PGD is not regulated in the USA are addressed, with consideration of factors such as funding for assisted reproductive technology treatmemt and the proximity of PGD to the contentious abortion debate. The obstacles that would need to be overcome in the USA for PGD to be regulated in the future are outlined. Then, the significance of the current divergence in PGD policy for patients around the world are discussed. Regulatory differences create opportunities for reproductive tourism, which result in legal, health and moral challenges. The paper concludes with comments on the need for policymakers around the world to balance respect for the characters and constitutions of their individual countries with appreciation of the needs of infertile patients across the globe.

摘要

与许多欧洲国家不同,美国没有关于使用植入前基因诊断(PGD)的法规。PGD是在一些生育治疗过程中使用的一种技术,用于根据基因选择胚胎。因此,PGD能够且确实被用于各种有争议的目的,包括性别选择、选择患有失聪等残疾的儿童,以及选择能够为患病亲属提供组织捐赠的“救星同胞”。由于美国政治和经济格局的特殊特征而缺乏监管,这对全球寻求PGD的患者具有伦理和实际影响。本文将美国PGD缺乏监管的情况与瑞士、意大利、法国和英国现有的PGD政策进行了对比。探讨了美国PGD不受监管的主要原因,同时考虑了诸如辅助生殖技术治疗的资金以及PGD与有争议的堕胎辩论的接近程度等因素。概述了美国未来对PGD进行监管需要克服的障碍。然后,讨论了当前PGD政策差异对全球患者的意义。监管差异为生殖旅游创造了机会,这带来了法律、健康和道德挑战。本文最后评论了世界各地政策制定者需要在尊重本国特点和宪法与理解全球不孕患者需求之间取得平衡。

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