Oxford University Hospital, Headington, Oxford, OX3 7LJ, UK,
Arch Gynecol Obstet. 2014 Mar;289(3):657-62. doi: 10.1007/s00404-013-3023-5. Epub 2013 Sep 12.
To review the outcomes of pelvic exenterative surgery done with a palliative intent and evaluate its role in relapsed gynaecology malignancies.
This is a retrospective cohort study between April 2009 and May 2012 in Oxford Gynaecological Cancer Centre. Patients were identified from the oncology surgical database.
18 patients were identified with a mean age 54 (26-79) years, who underwent surgery for symptomatic recurrent cancer. All except one patient had radiotherapy prior to surgery. 12 patients had cervical cancer, five had vulval cancer and one had endometrial cancer. About half of the patients had major surgical complications; however, majority was patients satisfied with the outcome.
Pelvic exenteration in this context carries considerable morbidity and in this series achieved good symptom control with a mean overall survival of 11 months. Careful patient selection, adequate counselling and ongoing support are imperative of successful outcome.
回顾以姑息为目的进行的盆腔根治性切除术的结果，并评估其在复发性妇科恶性肿瘤中的作用。
这是 2009 年 4 月至 2012 年 5 月在牛津妇科癌症中心进行的回顾性队列研究。从肿瘤外科数据库中确定患者。
18 名患者平均年龄 54（26-79）岁，因症状性复发性癌症接受手术。除一名患者外，所有患者在手术前均接受过放疗。12 例为宫颈癌，5 例为外阴癌，1 例为子宫内膜癌。约一半的患者发生严重手术并发症；然而，大多数患者对结果满意。
在这种情况下，盆腔根治性切除术具有相当大的发病率，本系列患者的总体生存时间为 11 个月，平均生存时间为 11 个月，症状控制良好。成功的结果需要对患者进行仔细的选择、充分的咨询和持续的支持。
