在突尼斯人群中，C4B基因座处一个新的C4B*1,12重复与BF*S07相关。
A new duplication C4B*1,12 at the C4B locus associated with BF*S07 in a Tunisian population.
作者信息
Gorgi Y, Arnold D, Uring-Lambert B, Bardi R, Ayed K, Hauptmann G
机构信息
Immunology Laboratory, Tunis, Tunisia.
出版信息
Tissue Antigens. 1990 May;35(5):217-9. doi: 10.1111/j.1399-0039.1990.tb01786.x.
Abstract
Twenty-five Tunisian families were analyzed for their complement alleles in order to detect duplications at the C4 loci. In this population, the most characteristic duplications are C4A2, B1.12 or C4A1, B1,12 always associated with BFS07 and C2C. This previously undescribed C4B1,12 duplication was found in seven families, five times in association with HLA-A2, B50.
摘要
对25个突尼斯家庭的补体等位基因进行了分析，以检测C4基因座的重复情况。在这个群体中，最具特征性的重复是C4A2、B1.12或C4A1、B1.12，它们总是与BFS07和C2C相关联。这种以前未描述过的C4B1.12重复在7个家庭中被发现，其中5次与HLA-A2、B50相关联。
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