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[对供血者血液进行抗HIV筛查。1986 - 1988年供血者筛查经验]

[Screening of donor blood for anti-HIV. Experiences from blood donor screening 1986-1988].

作者信息

Schmidt K W, Dickmeiss E

机构信息

Statens Seruminstitut, København, epidemiologisk afdeling.

出版信息

Ugeskr Laeger. 1990 Sep 3;152(36):2552-6.

PMID:2402841
Abstract

During the period 1986-1988, approximately 1,200,000 portions of blood were anti-HIV screened in Denmark. A total of 19 donors were found to be anti-HIV positive and no increase in the frequency of anti-HIV blood donors has been observed during this period. At a subsequent interview, nine out of these 19 donors (47%) were shown to have risk factors for HIV infection. During the same period, a total of 12 cases of transfusion-associated HIV infection were found at follow-up control of recipients of blood from previous donations from donors demonstrated to be positive after 1986. Four of the cases were demonstrated to be positive by blood donor screening and eight in other ways. Finally, five cases of transfusion-associated HIV infection in recipients have been reported where no positive donor could be identified. One case of HIV infection could be attributed to transfusion with screened anti-HIV negative blood. On the basis of information from blood donor screening, it is concluded that the risk that a screened anti-HIV negative blood portion in Denmark can transmit HIV infection is less than one per 400,000.

摘要

在1986年至1988年期间,丹麦对约120万份血液进行了抗HIV筛查。共发现19名献血者抗HIV呈阳性,在此期间未观察到抗HIV献血者频率增加。在随后的访谈中,这19名献血者中有9名(47%)被证明有HIV感染风险因素。在同一时期,对1986年后献血者检测呈阳性的既往献血受血者进行随访控制时,共发现12例输血相关HIV感染病例。其中4例通过献血者筛查呈阳性,8例通过其他方式呈阳性。最后,报告了5例受血者输血相关HIV感染病例,其中无法确定阳性献血者。有1例HIV感染可归因于输注经筛查抗HIV阴性的血液。根据献血者筛查信息,得出结论:丹麦经筛查抗HIV阴性的血液成分传播HIV感染的风险低于每40万分之一。

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