Weismann K, Arrøe M
Bispebjerg Hospital, København, dermato-venerologisk afdeling A.
Ugeskr Laeger. 1990 Sep 3;152(36):2571-2.
A premature infant with a birth-weight of 1,218 g developed severe zinc depletion about two months after birth. He had received his mother's breast-milk which was found to have a low zinc content of about 5 mumol/l. The clinical symptoms of zinc deficiency included stunted growth, catarrhal symptoms and a characteristic eczematous eruption on the face and diaper region known as acrodermatitis. Serum zinc was lowered (6.8 mumol/l) and so was serum alkaline phosphatase activity. Oral zinc sulphate supplementation, initially 22.5 mg daily and subsequently 11 mg zinc daily, had a prompt effect on the patient's well-being and the skin was restored to normal after about a week.
一名出生体重为1218克的早产儿在出生后约两个月出现严重的锌缺乏。他一直食用母乳，经检测母乳中锌含量较低，约为5微摩尔/升。锌缺乏的临床症状包括生长发育迟缓、卡他症状以及面部和尿布区域出现的特征性湿疹样皮疹，即肢端皮炎。血清锌水平降低（6.8微摩尔/升），血清碱性磷酸酶活性也降低。口服硫酸锌补充剂，最初每日22.5毫克，随后每日11毫克锌，对患者的健康状况产生了迅速的影响，大约一周后皮肤恢复正常。
