Saeed Bassam
Kidney Hospital, Damascus, Syria.
Saudi J Kidney Dis Transpl. 2013 Sep;24(5):1031-8. doi: 10.4103/1319-2442.118089.
The objective of this study was to evaluate the current activity of pediatric versus adult kidney transplantation activity in the Arab world. A questionnaire was mailed to all kidney transplant centers in Arab countries to collect data on the kidney transplant activity in a recent single year. Three thousand three hundred and nine kidney transplants were performed in one year, with a transplant rate of 9.5 per million populations (PMP); 298 were performed for children with a pediatric kidney transplant (PKT) rate of 0.87 PMP, which is much lower than that of developed countries where it mostly ranges from 5 to 10. The pediatric share of all transplants is 9%, which is twice as high as that of European children. Kidney transplant programs in most Arab countries rely exclusively on living donors as there is a severe shortage of deceased donors. 93.5% of all transplants, combined adult and pediatric, were from living donors. Deceased transplant activity in Arab countries accounts for 14-31% of all transplants in the three countries with deceased donor programs. Of the 212 adult and pediatric transplants that were performed from deceased donors in eight countries, only 29 cases were for pediatric recipients. Deceased PKT is available in the Kingdom of Saudi Arabia (KSA), Tunisia and Kuwait. Surprisingly, the PKT share was not better in the countries with higher overall kidney transplant rate and or in those where deceased transplant was available. PKT is still inactive in most Arab countries and mostly relies on living donors. The lack of well-developed deceased donor programs is the main issue to be addressed.
本研究的目的是评估阿拉伯世界儿科与成人肾脏移植活动的当前情况。向阿拉伯国家的所有肾脏移植中心邮寄了一份问卷,以收集最近一年肾脏移植活动的数据。一年中进行了3309例肾脏移植,移植率为每百万人口9.5例(PMP);其中298例为儿童肾脏移植(PKT),儿童肾脏移植率为0.87 PMP,远低于发达国家,发达国家的该比率大多在5至10之间。儿科移植在所有移植中的占比为9%,是欧洲儿童占比的两倍。大多数阿拉伯国家的肾脏移植项目完全依赖活体供体,因为尸体供体严重短缺。所有移植(包括成人和儿科)中,93.5%来自活体供体。在有尸体供体项目的三个国家,阿拉伯国家的尸体移植活动占所有移植的14%至31%。在八个国家进行的212例成人和儿科尸体供体移植中,只有29例是给儿科受者的。沙特阿拉伯王国(KSA)、突尼斯和科威特提供儿科尸体肾脏移植。令人惊讶的是,在总体肾脏移植率较高和/或有尸体移植的国家,儿科肾脏移植的占比并没有更好。大多数阿拉伯国家的儿科肾脏移植仍然不活跃,且大多依赖活体供体。缺乏完善的尸体供体项目是需要解决的主要问题。