Barth V, Büttner W
Klinik für Nephrologie und Urologie, Bezirkskrankenhauses Aue, DDR.
Zentralbl Allg Pathol. 1990;136(4):317-21.
Described in this paper are morphological and morphometric alterations that occurred to the remaining testicles in patients who had undergone chemotherapy or radiotherapy for malignant testicular tumours, with findings, on average, being recorded 4.5 years after treatment. Qualitative histological investigations of testicular tissue exhibited differentiated characteristics, with radiotherapy resulting in significantly stronger phenomena. Epithelial height was clearly reduced in conjunction with increase in wall thickness, especially after radiotherapy. Tubular lumens, in the wake of radiotherapy, were more often filled with hyalin than after chemotherapy. Unambiguous evidence was produced to impairment of fertility in response to both chemotherapy and radiotherapy.
本文描述了患有恶性睾丸肿瘤且接受过化疗或放疗的患者剩余睾丸所发生的形态学和形态测量学改变，平均在治疗后4.5年记录结果。对睾丸组织进行的定性组织学研究呈现出不同特征，放疗导致的现象更为明显。上皮高度明显降低，同时管壁厚度增加，尤其是在放疗后。放疗后，管腔比化疗后更常充满透明质。有明确证据表明化疗和放疗均会损害生育能力。
