Okdemir Deniz, Hatipoglu Nihal, Kurtoglu Selim, Akın Leyla, Kendirci Mustafa
J Pediatr Endocrinol Metab. 2014 Jan;27(1-2):175-9. doi: 10.1515/jpem-2013-0308.
Isolated premature thelarche is the breast development in the absence of other secondary sex characteristics in prepubertal girls. Fennel is a plant which contains a phytoestrogen called anethole as an active ingredient.
Here, we report a case of a 12-month-old girl who showed breast development that became apparent in the last 3 months. Her medical history revealed that she was given two to three teaspoons of fennel tea by her mother every day for restlessness for the last 6 months. Isolated premature thelarche was diagnosed based on physical and laboratory findings. On follow-up, after cessation of fennel consumption, the breast development of the patient regressed gradually and became normal by the end of 1 year.
Reporting this case, we want to emphasize the importance of awareness of fennel tea, a commonly used plant in babies, as a preventable cause of premature thelarche.
单纯性性早熟乳房过早发育是指青春期前女孩在没有其他第二性征的情况下出现乳房发育。茴香是一种植物,其活性成分包含一种称为茴香脑的植物雌激素。
在此,我们报告一例12个月大的女孩,其乳房发育在过去3个月中变得明显。她的病史显示,在过去6个月里,她的母亲每天给她喝两到三茶匙茴芹茶来治疗烦躁不安。根据体格检查和实验室检查结果诊断为单纯性性早熟乳房过早发育。随访发现,停止饮用茴芹茶后,患者的乳房发育逐渐消退,到1岁末恢复正常。
报告该病例是想强调,要认识到茴芹茶这种婴儿常用植物是性早熟乳房过早发育的一个可预防原因。