Suppr超能文献

暴露的无差异错误分类是否总是会使真实效应朝着无效值偏倚?

Does nondifferential misclassification of exposure always bias a true effect toward the null value?

作者信息

Dosemeci M, Wacholder S, Lubin J H

机构信息

Epidemiology and Biostatistics Program, National Cancer Institute, Rockville, MD 20892.

出版信息

Am J Epidemiol. 1990 Oct;132(4):746-8. doi: 10.1093/oxfordjournals.aje.a115716.

Abstract

The authors present some examples to demonstrate that in certain nondifferential misclassification conditions with polychotomous exposure variables, estimates of odds ratios for categories at intermediate level of risk can be biased away from the null or can change direction. In addition, the authors present two examples to demonstrate that the slope of the dose-response trend for the true distributions can change direction, creating a false inverse trend, even if the misclassification is nondifferential.

摘要

作者列举了一些例子来证明,在具有多分类暴露变量的某些无差异错误分类情况下,中等风险水平类别比值比的估计值可能会偏离无效值,或者可能会改变方向。此外,作者还给出了两个例子来证明,即使错误分类是无差异的,真实分布的剂量反应趋势斜率也可能会改变方向,从而产生错误的反向趋势。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验