关于非差异偏倚方向的误解。
Misconceptions About the Direction of Bias From Nondifferential Misclassification.
出版信息
Am J Epidemiol. 2022 Jul 23;191(8):1485-1495. doi: 10.1093/aje/kwac035.
Abstract
Measurement error is pervasive in epidemiologic research. Epidemiologists often assume that mismeasurement of study variables is nondifferential with respect to other analytical variables and then rely on the heuristic that "nondifferential misclassification will bias estimates towards the null." However, there are many exceptions to the heuristic for which bias towards the null cannot be assumed. In this paper, we compile and characterize 7 exceptions to this rule and encourage analysts to take a more critical and nuanced approach to evaluating and discussing bias from nondifferential mismeasurement.
摘要
测量误差在流行病学研究中普遍存在。 流行病学家通常假设研究变量的测量误差与其他分析变量无差异，然后依靠启发式方法“非差异分类错误将使估计值偏向于零”。 但是，对于启发式方法，存在许多例外情况，不能假设对零的偏差。 在本文中，我们汇编并描述了该规则的 7 个例外情况，并鼓励分析师采取更具批判性和细微差别的方法来评估和讨论非差异测量误差引起的偏差。
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