白喉抗体和 T 淋巴细胞计数在感染 HIV-1 的患者中。
Diphtheria Antibodies and T lymphocyte Counts in Patients Infected With HIV-1.
机构信息
Instituto de Biologia do Exército , Rio de Janeiro, RJ , Brasil ; Universidade do Estado do Rio de Janeiro, Faculdade de Ciências Médicas, Departamento de Microbiologia, Imunologia e Parasitologia , Rio de Janeiro, RJ , Brasil.
出版信息
Braz J Microbiol. 2012 Jul;43(3):946-50. doi: 10.1590/S1517-838220120003000014. Epub 2012 Jun 1.
We assessed the IgG levels anti-diphtheria (D-Ab) and T cell counts (CD4+ and CD8+) in HIV-1 infected subjects undergoing or not highly active antiretroviral therapy (HAART). Approximately 70% of all HIV-1 patients were unprotected against diphtheria. There were no differences in D-Ab according to CD4 counts. Untreated patients had higher D-Ab (geometric mean of 0.62 IU/ml) than HAART-patients (geometric mean of 0.39 IU/ml). The data indicated the necessity of keeping all HIV-1 patients up-to-date with their vaccination.
我们评估了正在接受或未接受高效抗逆转录病毒治疗（HAART）的 HIV-1 感染患者的抗白喉（D-Ab） IgG 水平和 T 细胞计数（CD4+ 和 CD8+）。大约 70%的所有 HIV-1 患者对白喉没有保护作用。D-Ab 与 CD4 计数无关。未经治疗的患者的 D-Ab （几何平均值为 0.62IU/ml）高于 HAART 患者（几何平均值为 0.39IU/ml）。这些数据表明有必要让所有 HIV-1 患者及时更新他们的疫苗接种情况。
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