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胎儿磁共振成像中的脊髓神经管缺陷。

Spinal neural tube defects on in utero MRI.

机构信息

Department of Neuroradiology, Royal Hallamshire Hospital, Sheffield, UK.

出版信息

Clin Radiol. 2013 Dec;68(12):e715-22. doi: 10.1016/j.crad.2013.07.019. Epub 2013 Sep 10.

Abstract

Spinal neural tube defects are a heterogeneous group of disorders, which remain relatively common, with a prevalence of 1-2 per 1000 live births despite advances in maternal antenatal care. They range from mild disorders with limited neurodevelopmental sequelae to extensive abnormalities with significant morbidity and mortality. The advent of in utero magnetic resonance imaging has enabled accurate anatomical characterization of an increasing number of abnormalities with increasing confidence. Recognition of the salient radiological features of these disorders and their relationship to the embryogenesis of the spinal cord and its coverings is now possible. This review describes the radiological appearances of these disorders with examples from Fetal Imaging Unit, University of Sheffield to illustrate the key anatomical and radiological features to aid the radiologist in their recognition.

摘要

脊髓神经管缺陷是一组异质性疾病,尽管孕产妇产前保健有所进步,但仍相对常见,每 1000 例活产中就有 1-2 例。它们的范围从轻度疾病伴有有限的神经发育后遗症到广泛的异常,具有显著的发病率和死亡率。宫内磁共振成像的出现使得越来越多的异常能够以越来越高的置信度进行准确的解剖学特征描述。现在可以识别这些疾病的显著放射学特征及其与脊髓及其覆盖物的胚胎发生的关系。本综述描述了这些疾病的放射学表现,并举例说明了谢菲尔德大学胎儿成像科的表现,以说明有助于放射科医生识别这些疾病的关键解剖学和放射学特征。

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