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对西班牙患者的 Clinically Useful Depression Outcome Scale(CUDOS)进行心理测量学分析。

A psychometric analysis of the Clinically Useful Depression Outcome Scale (CUDOS) in Spanish patients.

机构信息

Servei de Psiquiatria, Hospital de la Santa Creu i Sant Pau, Institut d'Investigació Biomèdica Sant Pau (IIB Sant Pau), Barcelona, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Spain.

出版信息

J Affect Disord. 2013 Dec;151(3):920-3. doi: 10.1016/j.jad.2013.08.007. Epub 2013 Aug 17.

DOI:10.1016/j.jad.2013.08.007
PMID:24035487
Abstract

BACKGROUND

Psychometrically sound and time-efficient scales that measure depressive symptoms are essential for research and clinical practice. This study was aimed at exploring the psychometric properties of the Spanish version of the Clinically Useful Depression Outcome Scale (CUDOS) in a clinical sample.

METHOD

Participants were 162 patients (72% women) with a mood disorder (86% diagnosed as major depressive disorder). Depressive symptoms were assessed by means of the CUDOS, the Beck Depression Inventory (BDI), and two interviewer-rated instruments: the 17-item Hamilton Depression Rating Scale (HDRS17) and the Clinical Global Impression-Severity (CGI-S) scale. Dimensionality, internal consistency, test-retest reliability, construct validity, criterion validity, and responsiveness to change of the CUDOS were explored.

RESULTS

The CUDOS exhibited a one-factor structure which accounted for 55.7% of the variance, and excellent results for internal consistency (Cronbach's alpha=0.93), for test-retest reliability (intraclass correlation coefficient=0.84) and for convergent validity [HDRS17 (r=0.77), CGI-S (r=0.73) and BDI (r=0.89)]. The ability of the CUDOS to identify patients in remission was high (area under ROC curve=0.96). Its responsiveness to change was also highly satisfactory: patients with greater clinical improvement showed a greater decrease in CUDOS scores (p<0.001).

LIMITATIONS

Diagnoses, even though made by expert clinicians, were established as part of routine clinical practice. Generalizability of the findings beyond the study sample is unknown.

CONCLUSIONS

The findings suggest that the Spanish version of the CUDOS is valuable as a brief and psychometrically sound self-report instrument to assess depressive symptoms in research and in clinical practice.

摘要

背景

用于研究和临床实践的、具有良好心理测量学特性且省时的抑郁症状量表至关重要。本研究旨在探索临床样本中,临床上有用的抑郁结局量表(CUDOS)的西班牙版本的心理测量特性。

方法

参与者为 162 名(72%为女性)患有心境障碍(86%被诊断为重度抑郁症)的患者。使用 CUDOS、贝克抑郁量表(BDI)和两种由评估者评定的工具:汉密尔顿抑郁评定量表 17 项(HDRS17)和临床总体印象-严重程度(CGI-S)量表评估抑郁症状。研究了 CUDOS 的维度、内部一致性、重测信度、结构效度、效标效度和对变化的反应性。

结果

CUDOS 表现出一个可解释 55.7%方差的单因素结构,内部一致性(Cronbach's alpha=0.93)、重测信度(组内相关系数=0.84)和聚合效度[HDRS17(r=0.77),CGI-S(r=0.73)和 BDI(r=0.89)]均表现出极佳的结果。CUDOS 识别缓解患者的能力较高(ROC 曲线下面积=0.96)。其对变化的反应性也非常令人满意:临床改善较大的患者 CUDOS 评分下降幅度更大(p<0.001)。

局限性

诊断虽然由专家临床医生做出,但作为常规临床实践的一部分。研究样本之外的发现的可推广性未知。

结论

研究结果表明,CUDOS 的西班牙语版本是一种有价值的简短且具有良好心理测量特性的自评工具,可用于研究和临床实践中评估抑郁症状。

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